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Get Injectable Results Without Spending Thousands Or Looking Done
This PDRN Treatment Triggers Your Skin's Natural Regeneration From Home
  • Visibly Smoother, Tighter Skin
  • Natural-Looking Transformation
  • Just 5 Minutes Twice A Month
  • Total Privacy & Control At Home
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150-Day Money Back Guarantee
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Dermatologist Approved
"I highly recommend the Derm™ PDRN Micro-Infusion Treatment. Its advanced formula with Salmon DNA (PDRN), delivers visible skin regeneration, deep hydration, and barrier support."
Dr. Elena Dinkollari, Certified Dermatologist
150-DAY MONEY BACK GUARANTEE
If you’re not absolutely thrilled with the results, we will refund every single penny of your investment.
FAST & FREE SHIPPING ON ALL THE ORDERS
We provide fast & free shipping and handling on all orders.
PHARMACEUTICAL GRADE FACILITY
Produced in sterile ISO certified labs using pharmaceutical-grade ingredients and processes.
You Are Just 5-Minutes Away From Younger-Looking Skin Without Botox Or Fillers...

Clinic Injections Are NOT Your Only Option
You've been researching injectables for months. 

You know the costs ($2,000-4,000 yearly, forever). You've bookmarked med spas. 

But you can't book it. 

Because one bad injector kills your credibility. The frozen look. The "work done" whispers. 

Becoming the cautionary tale instead of the authority. 

Meanwhile, you're losing ground. Lines deepen. Jawline softens. 

That "tired" look becomes permanent. 

And in your industry? "Looking tired" means "washed up." 

But there's a better option

The same pharmaceutical-grade PDRN clinics charge $400-800 for is now available at home with:
Complete privacy: Nobody knows.
Natural results: You look refreshed, not "done."
One-time investment: Not $4,000 every year.
Real collagen regeneration that gives you back your face—without the risks that kept you paralyzed.
Introducing: The PDRN Advanced Micro-Infusion System
To give women an alternative to expensive clinic visits, we created a simple at-home device that delivers pharmaceutical-grade PDRN directly to your skin's collagen layer...

Without expensive appointments, obvious results, or anyone knowing. 

This system combines precision micro-channels and pharmaceutical PDRN serum that reaches 0.5mm deep where aging actually occurs.

This is the exact depth where your fibroblasts produce collagen and elastin. 

The PDRN triggers your skin's natural regeneration process which helps smooth fine lines & wrinkles, lift sagging skin, and restore firmness, giving you clinic-like results from the privacy of home.
Approved by a Certified Dermatologist & Skincare Formulator

Award-Winning Expertise
40 Under 40
Expert in Science-backed skincare
Master in Medical Laboratory Technology
"As a Certified Organic Formulator with a professional diploma in Dermatology, I highly recommend the Derm™ PDRN Micro-Infusion Treatment. Its advanced formula with Salmon DNA (PDRN) delivers visible skin regeneration, deep hydration, and barrier support. A premium, results-driven treatment suitable for professional and advanced skincare routines."
Dr. Elena Dinkollari
Dermatologist & certified skincare formulator with advanced training in General Dermatology from Bond University, Melbourne, specializing in science-backed, natural skincare formulations and skin health optimization.
Holistic Dermatology
Integrative Medicine
Anti-Aging Expert
How Fast Can I See Results?
The PDRN Micro-Infusion System begins triggering collagen production from the first use, of course, your skin won't transform overnight, however most users notice their skin feels tighter and looks more radiant after just the first treatment. 

After 2-4 treatments (4-8 weeks) you should see visible reduction in lines, lifted contours, and smoother texture - your camera confidence returns and your skin looks like it did years ago, naturally.
TRY RISK-FREE TODAY 👉
NOTE: Not Available on Amazon or eBay
How The PDRN Micro-Infusion System Works
The best part about the PDRN system is that it's so simple to use from home. 

First, attach the PDRN serum vial to the sterile 24K gold needle head, it clicks into place and you're ready to treat.

The second step is to gently stamp the device across your treatment areas following the included step-by-step guide. 

The treatment takes just 5 minutes. 

Complete privacy - do it in your bathroom, your bedroom, whenever works for you. 

With consistent use twice a month, deep collagen regeneration is triggered, smoothing lines, lifting sagging areas, and restoring firmness - giving you natural-looking results without anyone knowing you did anything.
Try It for 150 Days, 100% Risk-Free
Here's the deal: We believe in this system so much that we don't want you to spend a dime until you're 100% certain it works for you.

That's why we are offering a 150-day "Results or Refund" guarantee

Simply, get the PDRN Micro-Infusion System today, use it for 150 days, and then make your decision based on what you see in the mirror. If you are not absolutely thrilled with the results, we will issue you an immediate refund. 

In other words, you are only paying if you look in the mirror and see yourself again—smoother, lifted, and camera-ready.
They Did It Privately. 
No One Knew. 
 Here Are The Results. 
Fine Lines & Natural Radiance

Theresa R.
Verified Customer

Reverses early signs of aging
Softens smile lines & expression lines
Restores natural radiance & youthful glow
Hydration & Youthful Glow

Melanie G.
Verified Customer

Visibly smooths fine lines
Hydrates & plumps for a youthful look
Brightens & refreshes tired skin
Smile Lines & Forehead Lines

Susan A.
Verified Customer

Visibly smooths expression lines & forehead lines
Brightens & refreshes tired-looking skin
Refines texture for a naturally radiant glow
Get Younger-Looking Skin in Just 4 Easy Steps
Skin experts recommend twice a month application for optimal results
How It Works
Step 1
Prep Your Skin
Cleanse your face and pat dry. Make sure your skin is clean and ready to absorb.
Step 2
Attach & Prime
Twist the serum vial directly onto the microneedle head. Hold the device upside down for ~2 minutes to allow full serum flow into the needles.
Step 3
Stamp & Infuse
Gently press the device onto your skin, starting from the center of the face and moving outward with 50% overlap. Focus 2–3 passes over areas prone to fine lines, wrinkles, or loss of firmness.
Step 4
Let It Absorb
Pat any leftover serum onto the skin and leave it on overnight. Avoid makeup or sun exposure for 24 hours.
Every order comes with a step-by-step video guide and instructions.
Just 5 minutes every 2 weeks.
Powerful Ingredients That Transform Your Skin
PDRN (Salmon DNA)
Helps Support Skin Regeneration, Improving Firmness & Elasticity
CENTELLA ASIATICA
Helps Soothe Skin, Support Repair & Improve Resilience
NIACINAMIDE
Helps Energize Skin to Boost Radiance & Strengthens Barrier
PANTHENOL
Helps Calm, Nourish & Strengthen the Skin Barrier

HYALURONIC ACID
Helps Boost Moisture for Plumper, Smoother Skin
FORMULATED WITHOUT: Artificial colorants, fragrance, alcohol, or comedogenic ingredients. Cruelty free.
VIEW FULL INGREDIENTS LIST
Water, Glycerin, Butylene Glycol, Trehalose, Panthenol, Niacinamide, 1,2-Hexanediol, Hydroxyacetophenone, Cyclodextrin, Sodium DNA (Salmon DNA), Carbomer, Gentiana Scabra Root Extract, Sodium Hyaluronate, Arginine, Centella Asiatica Extract, Gardenia Florida Flower Extract, Phellodendron Amurense Bark Extract, Caprylyl Glycol, Mannitol, Madecassoside, Centella Asiatica Leaf Extract, Adenium Obesum Leaf Cell Extract, Asiaticoside, Soluble Collagen.
The PDRN Micro-Infusion System Is The Smarter, Safer Choice
It's private, affordable, and actually regenerates your skin instead of masking the problem.
PDRN Micro-Infusion System
REGENERATES, NOT MASKS
Triggers your own collagen production for lasting results.
ONE-TIME PURCHASE
Pay once, not every few months forever at the clinic.
COMPLETE PRIVACY
Do it at home without clinic visits, witnesses or judgment.
NATURAL-LOOKING RESULTS
No one will know you did anything. You just look refreshed.
NO DOWNTIME OR PAIN
5 minutes twice a month. No swelling, bruising, or recovery.
Clinic Injectables
TEMPORARY MASKING ONLY
Paralyzes muscles or fills space. Doesn't fix the root cause.
EXPENSIVE FOREVER
$400-800 per session, every 3-4 months. Never ends.
PUBLIC & EXPOSED
Clinic waiting rooms, parking lots where colleagues might see you.
RISK OF "DONE" LOOK
One bad injector and your career credibility is at risk.
PAINFUL & INVASIVE
Needle injections with swelling and bruising you have to explain to everyone.
What Our Clients Say
VISIBLE IMPROVEMENT
Smoothed Fine Lines
Verified Purchase
“I started noticing fine lines in my early 40s, and nothing I tried made a real difference. After three treatments, those lines are so much softer and my skin looks smoother, brighter, and more refreshed. Even my colleagues have commented that I look more rested!"
Ielaine N.
Purchased 3 PDRN Micro-Infusion System
VISIBLE IMPROVEMENT
Sagging Skin & Neck Wrinkles
Verified Purchase
"I'd been googling Botox prices for months but couldn't do it, way too expensive and honestly terrified someone at work would notice. Did 6 treatments with this and my jawline looks so much better. Best part? Not a single person has asked if I got work done. They just keep saying I look really good lately."
Regan R.
Purchased 3 PDRN Micro-Infusion System
VISIBLE IMPROVEMENT
Fine Lines & Skin Firmness
Verified Purchase
"The lines around my mouth were so deep I looked angry even when I wasn't. I was researching fillers but honestly the price scared me off. After 6 treatments those smoker lines are way less visible and my whole face just looks plumper somehow? My friend said 'Barbara, your skin looks really good lately' and had no clue I was doing anything. So glad I tried this first."
Barbara D.
Purchased 5 PDRN Micro-Infusion System
NOTE: Not Available on Amazon or eBay
New Year Limited Offer
Break Free From Expensive Clinic Injections and You'll Get:
  • 56% OFF - Save Up to $280 on Professional 5-Kit
    150-Day Results or Refund Guarantee
    FAST & FREE Shipping           
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Note : Not Available on Amazon or eBay
Dermatologist Approved
Fast & Free Shipping
150-Day Money Back Guarantee
24/7 Customer Service
Over 30,000 Happy Customers
100% SATISFACTION 
150-DAY MONEY BACK GUARANTEE
Your order today is protected by our iron-clad 150-day 100% money-back guarantee. If you don't see the smoother, lifted, younger-looking skin you were expecting, or if you're not thrilled with the results, then at any time in the next 150 days let us know and we will refund every single penny of your investment. No questions asked.
 Frequently Asked Questions 
When will I start seeing results?
Many users notice smoother, more hydrated skin after just one treatment — often describing a fresh glow and softer texture within 24–48 hours. That’s because the micro-infusion process immediately boosts hydration and wakes up your skin’s repair response. However, for visible, lasting improvement, we recommend completing at least 6 treatments over 3 months. Regular use may help support a firmer, more radiant look over time. Consistency matters more than speed — and we’re here to support you through that journey.
How does this work on deep wrinkles and sagging skin?
It combines precision micro-infusion with a clinically proven collagen-boosting serum powered by PDRN. The ultra-fine, painless 24K gold needles create micro-channels in your skin, allowing the serum to reach the deeper layers where collagen loss and structural changes cause wrinkles and sagging. This process stimulates new collagen and elastin production, helping to lift, firm, and smooth the skin from within — for a more youthful, resilient complexion over time.
How many treatments are included, and how often should I use it?
Each Micro Infusion System includes single-use sterile microneedle heads and serum vials. 

1-Month Supply → 2 treatments (2 needle heads and 2 serum vials) 
2-Month Supply → 4 treatments (4 needle heads and 4 serum vials) 
3-Month Supply → 6 treatments (6 needle heads and 4 serum vials) 

We recommend one session every 2 weeks to give your skin time to regenerate properly. This rhythm supports long-term collagen activation and minimizes irritation. After each session, it is recommended to dispose of the used needle head and apply any remaining serum on your skin. Each order comes with an easy to follow step-by-step video guideline.
Is it painful?
The device uses ultra-fine, sterile 24K gold microneedles designed to gently penetrate only the uppermost layer of skin. While they are long enough to trigger collagen and increase serum absorption, they are also thinner than a human hair, which makes the treatment very tolerable — even for beginners. You might feel a light tingling or pricking during application, especially in more sensitive areas. But there’s no dragging, tearing, or numbing required. Most people describe it as a gentle tapping sensation — and get used to it within seconds.
What is the length of the needles?
Derm’s micro-infusion system uses microneedles that are 0.5mm in length — ideal for what's called “epidermal needling.” This depth allows the serum to reach the upper dermis — the layer where fine lines begin and skin firmness starts to decline — without causing pain or requiring medical supervision. 

It’s long enough to: 
- Stimulate collagen and elastin production 
- Boost skin cell renewal for smoother texture 
- Enhance absorption of active ingredients up to 30× more effectively than topical application 

At the same time, it's short enough to avoid bleeding or downtime, making it perfectly safe for at-home use — even for beginners.
Is it suitable for sensitive or darker skin tones?
Yes. Our formula and delivery system are both designed to be non-comedogenic, non-irritating, and safe for all skin types and tones. We don’t use harsh acids, retinoids or bleaching agents. If your skin is extremely reactive, we recommend a patch test first, or consulting a dermatologist.
Will this also work on acne scars?
Yes — while it’s designed to target fine lines, wrinkles, and loss of firmness, the same technology can help improve the appearance of acne scars. Our ultra-fine, painless 24K gold needles create micro-channels in the skin, allowing the PDRN-powered serum to reach the deeper layers where both aging and scar texture originate. This stimulates collagen production, refines texture, and can visibly reduce the look of shallow scars over time.
What is the percentage of PDRN (Salmon DNA) inside the formula?
Our formula contains 0.2% PDRN — an ideal concentration for at-home use, especially when paired with micro-infusion, which enhances absorption compared to regular topical application. Because our system infuses the ingredients directly into the upper layers of the skin, the PDRN is absorbed more efficiently than it would be in a standard serum. 

This means: 
- 0.2% delivered through micro-infusion can be more effective in practice 
- Topical serums with higher percentages often remain mostly on the surface 
- You get meaningful results while keeping the formula gentle and safe 

 This balance ensures a treatment that is effective, well-tolerated, and suitable for consistent use at home.
Is this FDA approved?
The micro-infusion device itself is not FDA-approved yet. Our manufacturer is currently in the process of obtaining FDA 510(k) clearance for the microneedle stamp, but this review takes time and is still ongoing. 

The serum component is FDA-listed under MoCRA, which is the FDA’s regulation framework for cosmetic products. 

Both the device and serum are produced in an FDA-registered, GMP-certified, and ISO 22716–compliant facility, ensuring controlled production, sterile conditions, and consistent quality across every batch.
How long does redness or irritation last after a treatment? If I have a treatment on Friday night, will my skin look normal again by Monday?
Most people only notice slight redness immediately after treatment, which usually disappears within a few hours or at most a day. By Monday, the skin should return to normal, so it is advisable to undergo treatment on Friday evening. We also always recommend doing a patch test on your wrist and leaving it on for 24 hours.
What if you're allergic to fish?
Since PDRN is derived from salmon DNA, if you have a known fish allergy we recommend not using this product or first consulting with your doctor. Your safety always comes first.
Can I use it on active acne or open wounds?
We recommend waiting until active breakouts have calmed before using the device. Using microneedles on inflamed or broken skin may lead to irritation or delayed healing.
Can I use it on my neck, lips or other areas of the body?
Yes — it can be safely used on the neck, lips, and most areas of the body where you want to improve skin texture, smooth fine lines, or boost firmness. 
 
Many users apply it also to areas with: 
- Crepey skin on the décolleté 
- Fine lines and loss of firmness along the neck and jawline 
- Textural irregularities or dryness on the arms or hands 

For sensitive zones like lips and neck, apply with light pressure and follow our guided stamping technique. However, avoid using the device directly on the eyelids or waterline. We recommend keeping at least 1.5 inches (around 3 cm) away from the eyes to protect delicate skin. Every order includes a detailed step-by-step video guide to show you exactly how and where to apply it for best results.
What should I do after each treatment?
After each treatment, your skin is in “recovery mode” — and also more receptive to anything you apply. To protect your results and avoid irritation, we recommend the following: 

First 24 hours: 
 - Avoid makeup, sun exposure, and sweating (no gym, sauna or steam) 
- Do not apply active ingredients like retinol, acids, scrubs, or exfoliants 
- Keep skin clean and hydrated using a gentle, fragrance-free moisturizer 
- Try not to touch your face, especially with unwashed hands 

Day after: 
- Wash your face with a mild cleanser, pat dry, and moisturize 
- If you go outside, apply a high-quality, non-comedogenic SPF 

What’s normal: 
It’s common to experience light redness, dryness or a tight feeling for a few hours. Some users may notice slight flaking or peeling a few days later — a sign your skin is renewing. 

Pro tip: 
Your skin absorbs ingredients up to 3x better after infusion, so avoid applying anything harsh during this window. Stick to calming, barrier-repair formulas only. Most users return to their full skincare routine within 48 hours — but you may not even feel the need for much. The serum does most of the work.
Can I apply Hyaluronic Acid, moisturizer, or my usual skincare after treatment?
Yes — but with a few important guidelines. Right after your treatment, your skin is more permeable and sensitive. This means ingredients absorb better, but it also makes your skin more reactive. 

Here’s what you can use: 
- Hyaluronic acid or hydrating moisturizers: apply in the evening after treatment to boost hydration and support healing 
- Fragrance-free, calming creams (e.g., with panthenol, ceramides, or Centella) are also recommended 

Here’s what to avoid for 24–48 hours: 
- Retinol (Vitamin A) 
- Exfoliating acids (glycolic, lactic, salicylic) 
- Vitamin C serums, scrubs, or strong actives 
- Any skincare with fragrance or alcohol
How do I use Derm’s Micro-Infusion System?

It’s simple and takes just a few minutes. Whether you're new to skincare or an experienced user, you’ll find the process easy to follow — and incredibly rewarding. Here’s how it works: 

1. Prep Your Skin 
Start with a freshly cleansed face. Gently pat dry and ensure your skin is free of any products. 

2. Attach & Prime 
Twist the serum vial directly onto the microneedle head. Then hold the device upside down for about 2 minutes, allowing the serum to fully saturate the needles. 

3. Stamp & Infuse 
Gently press the device onto your skin, beginning at the center of the face and working outward. Use a 50% overlap between stamps, and repeat 2–3 passes over areas prone to fine lines, wrinkles, or loss of firmness. Avoid stamping directly over active breakouts. 

4. Let It Absorb 
Pat any leftover serum onto your face and neck. Leave the serum on overnight, and avoid makeup or sun exposure for the next 24 hours. The entire treatment takes 5–10 minutes. Every order includes a step-by-step video guide to help you use it with confidence — even if it’s your first time.

Can I reuse the needle heads?
No — and you shouldn't. Each microneedle head is sterile and single-use, just like in clinical settings. Reusing the same head compromises hygiene, blunts the needles, and increases the risk of irritation or infection. We include a fresh head for each treatment — no need to guess or clean.
Can I use my own serum with the device?
We don’t recommend using third-party serums. The DERM formula was developed to work with micro-infusion: it’s lightweight, fast-absorbing, and enriched with actives like PDRN, Niacinamide, and Panthenol. Other serums may contain irritants or molecules too large to penetrate through micro-channels — wasting your treatment or even causing sensitivity.
Once you have used long enough to get the desired result, do you need to continue using?
Once you’ve reached your desired results, you don’t need to use it as often — many switch to a maintenance rhythm, like once a month. The results typically last several weeks, depending on your skin type, age, and skincare routine. Regular use helps prolong and maintain the effect over time.
What’s the difference between this and microneedling rollers?
Rollers create micro-injuries — but don’t deliver ingredients into the skin. Our Micro Infusion System not only creates the micro-channels, it also infuses a clinically active serum directly where aging forms. 

Plus: 
- It uses sterile, single-use heads 
- Rollers often get reused, increasing risk of irritation & bacteria 
- Our stamping mechanism is more precise, less damaging
Can I use it if I’ve had laser, filler or other treatments?
Yes, but we suggest waiting at least: 

- 2 weeks after fillers / Botox 
- 4/6 weeks after laser treatments 

And as always — check with your dermatologist if you're under clinical care.
Do I need to do anything special to prep my skin?
No extensive prep needed. Just clean your face thoroughly, make sure your hands are clean, and you're good to go. Optionally, apply a gentle toner or hydrating mist before starting to help serum spread evenly.
Is this just for women?
Absolutely not. Signs of aging affect everyone — and this treatment is designed to work for all genders and all skin types. We see incredible results with men who want to smooth fine lines, improve skin texture and regain confidence without a 10-step routine or clinic visits.
How does your money-back guarantee work?
Our money-back guarantee ensures that if you are not satisfied with your purchase, you can return the item within 150 days of receipt for a full refund. Simply contact our customer service team to initiate the return process, and follow the provided instructions. Once we receive the returned item, we will process your refund within 5-7 business days. For returns, please email us at support@try-derm.com
The information presented on this website is not intended as specific medical advice and is not a substitute for professional treatment or diagnosis. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
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